Heterogeneity of Template RNA in Adrenal Glands

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Science  19 Aug 1966:
Vol. 153, Issue 3738, pp. 896-897
DOI: 10.1126/science.153.3738.896


Template RNA in adrenal glands appears to be heterogeneous in stability. The RNA that regulates synthesis of a large fraction of adrenal protein has a turnover time of 4 hours or less. The remainder of adrenal-protein synthesis, including synthesis of protein that mediates the rapid steroidogenic response to ACTH, depends on RNA with considerably greater stability.