Surface Area of Human Erythrocyte Lipids: Reinvestigation of Experiments on Plasma Membrane

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Science  26 Aug 1966:
Vol. 153, Issue 3739, pp. 1010-1012
DOI: 10.1126/science.153.3739.1010


Ratios of the lipid monolayer area to the erythrocyte surface area are 2:1 at low surface pressures and approach 1: 1 at collapse pressures. Un saturated phospholipids in cholesterol-phospholipid complexes of membrane ex tracts resemble their saturated derivatives at collapse pressures. Area ratio and phospholipid area data are related by an equation that tests hypothetical values for molecular areas used in membrane models.