Ascending and Descending Cholinergic Fibers in Cat Spinal Cord: Histochemical Evidence

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Science  23 Sep 1966:
Vol. 153, Issue 3743, pp. 1543-1544
DOI: 10.1126/science.153.3743.1543


The distribution of fibers staining for cholinesterase in the spinal cord of the cat was examined after hemisection at the level of the third cervical segment (C3), of the tenth thoracic segment (Ti 0), or of the first lumbar segment (LI). An accumulation of cholinesterase was found in many fibers of the cord both rostral and caudal to the lesion, the distribution being different in the two regions. These experiments indicate that there are ascending and descending cholinergic fibers in cat spinal cord.