Species Specific Effect of Acetylcholine on Bivalve Rectums

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Science  25 Nov 1966:
Vol. 154, Issue 3752, pp. 1015-1017
DOI: 10.1126/science.154.3752.1015


The pharmacology of acetylcholine and 5-hydroxytryptamine on the rectums of Katelysia rhytiphora and K. scalarina was found to be similar, in general, to that of other bivalves. However, while acetylcholine causes a fast twitch in the rectum of K. rhytiphora, the activity and tone of the K. scalarina rectum are depressed except at high concentrations of the drug. The two species can be distinguished by these responses, and, therefore, these rectums are useful experimental objects for studying the physiology of molluscan visceral muscle.