Curare as a Neuromuscular Blocking Agent in Insects

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Science  25 Nov 1966:
Vol. 154, Issue 3752, pp. 1023-1024
DOI: 10.1126/science.154.3752.1023


Topical application of curare produced no effects on electrical activity in single flight-muscle fibers of the fly Sarcophaga. However, the intraabdominal injection of curare induced a neuromuscular block similar to that described for vertebrates. The general refractoriness of some insects to chemical agents may well be due to the method of application.