Multiple Gene Loci for the Monomeric Hemoglobin of the Hagfish (Eptatretus stoutii)

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Science  25 Nov 1966:
Vol. 154, Issue 3752, pp. 1034-1035
DOI: 10.1126/science.154.3752.1034


The fact that members of the subclass Cyclotomata possess monomeric hemoglobin molecules has been known for some time. Electrophoresis of hemolysates from 12 hagfish (Eptatretus stoutii) revealed five hemoglobin phenotypes with four to six distinct zones of hemoglobin. Each zone is believed to represent a monomer containing one heme group on a single polypeptide chain with a molecular weight of approximately 18,000. It is postulated that these monomers are controlled by genes at four loci.