Rapid and Marked Inhibition of Rat-Liver RNA Polymerase by Aflatoxin B1

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Science  02 Dec 1966:
Vol. 154, Issue 3753, pp. 1205-1206
DOI: 10.1126/science.154.3753.1205


From 15 minutes to 2 hours after the administration of aflatoxin B1 invivo there is a 35-to 70-percent inhibition of DNA-directed RNA synthesis. The inhibition was reversed 12 and 24 hours later.