Seizure Discharges Evoked in Vitro in Thin Section from Guinea Pig Hippocampus

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Science  20 Jan 1967:
Vol. 155, Issue 3760, pp. 341-342
DOI: 10.1126/science.155.3760.341


A thin section prepared from guinea pig hippocampus produced, in chloride-free medium, a train of seizure discharges in response to a single shock applied to the section. Generation of these discharges was ascribed to the lack of inhibitory processes in an absence of chloride ion.