Thyroxine Interaction with Actinomycin D and Possible Biological Implications

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Science  14 Apr 1967:
Vol. 156, Issue 3772, pp. 245-246
DOI: 10.1126/science.156.3772.245


Actinomycin D and thyroxine interact in solution (pH 8 to 10), as revealed by changes in the absorbance of actinomycin D. Thyroxine can prevent the growth-inhibitory effect of actinomycin D on Bacillus subtilis if it is present in a molar ratio of 3000 (thyroxine to actinomycin D).

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