Norepinephrine: Turnover in Rat Brains after Gonadectomy

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Science  15 Mar 1968:
Vol. 159, Issue 3820, pp. 1245
DOI: 10.1126/science.159.3820.1245


The rate at which 3H-norepinephrine disappears from rat braint increases after gonadectomy; the effect is observed 6 days after the operation and 24 hours after introduiction of the labeled mnaterial; it is not reprodluced by hypophysectomy. The content of endogenouis brain norepinephrinie does not decline after removal of the ovaries or testes; thus synlthesis of the catecholamine is probably increased by these procedures.

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