Crystal Structure of a Complex of Acridine, Cytosine, and Water (1: 1 : 1)

See allHide authors and affiliations

Science  21 Jun 1968:
Vol. 160, Issue 3834, pp. 1351-1352
DOI: 10.1126/science.160.3834.1351


X-ray structural analysis of a crystalline complex between acridine C13H9N, cytosine C4H5N3O, and water (1:1:1) has been completed. The cytosine and water molecules form a sheet-like structure through a series of hydrogen bonds. The acridine molecules are bound to this layer through a hydrogen bridge from the water to the ring nitrogen. The acridine molecules stack in a parallel fashion normal to the cytosine-water sheets, with an average interplanar spacing of 3.5 angstroms.

Stay Connected to Science