Hippocampal Correlates of Aversive Midbrain Stimulation

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Science  21 Jun 1968:
Vol. 160, Issue 3834, pp. 1363-1365
DOI: 10.1126/science.160.3834.1363


Hippocampal synchronization during aversive dorsal midbrain stimulation was observed in rats both in a conditioning procedure and under d-tubo-curarine paralysis. The results restrict the generality of previous reports which correlated hippocampal synchronization and desynchronization with approach and withdrawal behavior, respectively. Relative to the condition of free movement, curarization reduced the frequency of both "spontaneous" and dorsal midbrain-evoked synchronization, thus suggesting possible direct and indirect effects of d-tubocurarine on subcortical structures.

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