Rat Mammary Gland Differentiation in vitro in the Absence of Steroids

See allHide authors and affiliations

Science  05 Jul 1968:
Vol. 161, Issue 3836, pp. 59-60
DOI: 10.1126/science.161.3836.59


Mammary glands from several strains of immature female rats will form small lobules of alveoli when cultured in chemically defined media lacking steroid hormones but containing insulin and prolactin. The degree of lobulo-alveolar differentiation is increased if estradiol, progesterone, and aldosterone are also included in the culture media.

Stay Connected to Science