Actomyosin-Like Protein Isolated from Mammalian Brain

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Science  12 Jul 1968:
Vol. 161, Issue 3837, pp. 170-171
DOI: 10.1126/science.161.3837.170


A protein with characteristics similar to actomyosin has been isolated from whole brain of rat and cat. It is soluble in 0.6 molar potassium chloride and insoluble in 0.1 molar potassium chloride. It superprecipitates with magnesium ions and adenosine triphosphate. It has adenosine triphosphatase activity stimulated by either magnesium or calcium ions. Both superprecipitation and adenosine triphosphatase activity are inhibited by p-chloromercuribenzoate and Mersalyl but not by ouabain.

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