Histochemical Localization of Renal Trehalase: Demonstration of a Tubular Site

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Science  09 Aug 1968:
Vol. 161, Issue 3841, pp. 571-572
DOI: 10.1126/science.161.3841.571


Trehalase activity has been localized histochemically within the cortical tubules of the human, rabbit, and mouse kidneys. The specific localization of the enzyme supports the hypothesis that trehalase, in concert with a series of other enzymes which synthesize trehalose from glucose, functions in a mechanism for the reabsorption of glucose from the glomerular filtrate.

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