Drosophila melanogaster Treated with LSD: Absence of Mutation and Chromosome Breakage

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Science  16 Aug 1968:
Vol. 161, Issue 3842, pp. 694-696
DOI: 10.1126/science.161.3842.694


Injection of lysergic acid diethylamide in Drosophila melanogaster males induced no mutations or chromosome breaks in premeiotic, meiotic, or postmeiotic sperm. Tests included those for sex-linked lethals, sex-linked visibles, a specific visible (dumpy), and translocations. Some implications of these experiments are discussed.

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