Visual Pigment Renewal in the Mature Frog Retina

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Science  23 Aug 1968:
Vol. 161, Issue 3843, pp. 787-789
DOI: 10.1126/science.161.3843.787


It has been demonstrated by autoradiography that radioactive amino acids serve as precursors for proteins which are subsequently incorporated into retinal rod outer segment discs in mature animals. By the isolation and purification of visual pigment from retinas of adult frogs after injection of tritiated leucine and phenylalanine, it has been shown that at least part of this labeled protein consists of visual pigment (rhodopsin).

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