Breakdown and Assembly of Polyribosomes in Synchronized Chinese Hamster Cells

See allHide authors and affiliations

Science  23 Aug 1968:
Vol. 161, Issue 3843, pp. 791-793
DOI: 10.1126/science.161.3843.791


Polyribosomes were absent in metaphase Chinese hamster cells and were reassembled after mitosis. This assembly correlated temporally with formation of nuclear membrane and decondensation of chromatin, accounted for a threefold increased rate of protein synthesis, and occurred independently of de novo RNA synthesis, that is, it utilized preexisting messenger RNA.

Stay Connected to Science