Partial Hydroxylation of Certain Lysines In Collagen

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Science  23 Aug 1968:
Vol. 161, Issue 3843, pp. 796-798
DOI: 10.1126/science.161.3843.796


Peptides derived from the al chain of collagen have been isolated in small amounts and have been shown to differ from ones found in expected amounts only by substitution of hydroxylysine for lysine. This observation indicates that hydroxylation of these lysines by protocollagen hydroxylase has been effected to a very minor extent.

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