Ecdysones and Analogs: Effects on Development and Reproduction of Insects

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Science  13 Sep 1968:
Vol. 161, Issue 3846, pp. 1158-1160
DOI: 10.1126/science.161.3846.1158


Ingestion of certain synthetic ecdysone analogs inhibited larval growth and development in several species of insects, whereas 20-hydroxyecdysone was inactive or considerably less active. Natural 20-hydroxyecdysone and ponasterone A, and a synthetic ecdysone analog inhibited ovarian maturation and egg production in the adult housefly. These effects appeared to be related to hormonal activity.

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