Liver Adenine Nuldeotides: Fructose-Induced Depletion and Its Effect on Protein Synthesis

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Science  20 Sep 1968:
Vol. 161, Issue 3847, pp. 1253-1254
DOI: 10.1126/science.161.3847.1253


Intravenous administration of D-fructose to rats rapidly depletes liver adenosine triphosphate and inorganic phosphate; marked elevations of uric acid and allantoin in plasma follow. Concomitantly the incorporation of DL-leucine-1-14C into liver protein is almost completely inhibited.

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