Sarcomeric Oscillations in Frog Skeletal Muscle Fibers

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Science  27 Sep 1968:
Vol. 161, Issue 3848, pp. 1357-1358
DOI: 10.1126/science.161.3848.1357


Brief asynchronous, small-amplitude, cyclic, longitudinal displacements of the striations of frog skeletal muscle fibers were observed with ordinary light microscopy after application of caffeine and certain quaternary ammonium compounds. With time these oscillations became synchronized and evolved into peristaltic-like movements. The oscillations were influenced by sarcomere length, temperature, external concentration of calcium ions, membrane potential, and disruption of the transverse tubules.

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