Long-Lasting Hyperpolarization after Activity of Neurons in Leech Central Nervous System

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Science  11 Oct 1968:
Vol. 162, Issue 3850, pp. 279-281
DOI: 10.1126/science.162.3850.279-a


After a train of impulses, the membrane potential of sensory neurons may be increased for several minutes by an electrogenic pump. During this hyperpolarization, the sensitivity of the membrane potential to external potassium ions is increased, so that physiologically occurring increases in potassium concentration could influence synaptic processes.

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