Hydroxyindole-O-Methyl-Transferase Activity: Effect of Sympathetic Nerve Stimulation

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Science  18 Oct 1968:
Vol. 162, Issue 3851, pp. 367-368
DOI: 10.1126/science.162.3851.367


Stimulation of the preganglionic nerve trunk to the superior cervical ganglion causes a reduction in pineal hydroxyindole-O-methyl-transferase levels which is time-dependent. The results provide direct evidence for a role of afferent input in the control of pineal enzymatic activity.

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