Estrogen-Dependent Increase in Transfer RNA during Differentiation of the Chick Oviduct

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Science  01 Nov 1968:
Vol. 162, Issue 3853, pp. 567-568
DOI: 10.1126/science.162.3853.567


Estrogenic hormones induce morphologic and biochemical differentiation in the oviduct of the immature chick. Concomitant with the hormone-stimulated tissue growth, there was an increase in 4S RNA, as judged by polyacrylamide-gel electrophoresis, and a corresponding increase in cellular transfer RNA activity, as measured by the amino acid acceptor capacity. This system may be suitable for studying the relation of hormones to transfer RNA in a differentiating tissue.

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