Hypothalamic Stimulation of Growth Hormone Secretion

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Science  01 Nov 1968:
Vol. 162, Issue 3853, pp. 580-582
DOI: 10.1126/science.162.3853.580


Stimulation of the ventromedial hypothalamic nucleus in rats resulted in increased plasma growth hormone levels within 5 minutes, as measured by radioimmunoassay. Stimulation of the cerebral cortex was without effect. These observations confirm previous results involving destructive lesions and establish the ventromedial nucleus as a hypothalamic locus involved in the control of growth hormone secretion.

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