Dietary Regulation of Galactose-Metabolizing Enzymes: Adaptive Changes in Rat Jejunum

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Science  08 Nov 1968:
Vol. 162, Issue 3854, pp. 692-693
DOI: 10.1126/science.162.3854.692


The effects of dietary galactose, sucrose, fructose, glucose, casein, and fasting upon the activity of four galactose-metabolizing enzymes (galactokinase, galactose-1-phosphate uridyltransferase, uridine diphosphate galactose 4-epimerase, and galactose dehydrogenase) were studied in the jejunum of rats. Galactose produced the greatest increase in enzyme activity, fructose and sucrose produced effects intermediate between galactose and glucose, and casein produced a greater activity increase than fasting, but less than the sugars.

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