Tyrosine Transaminase: Development of Daily Rhythm in Liver of Neonatal Rat

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Science  29 Nov 1968:
Vol. 162, Issue 3857, pp. 999-1001
DOI: 10.1126/science.162.3857.999


The development of the 24-hour rhythm in tyrosine transaminase activity was studied in the liver of the neonatal rat. A recognizable rhythm appears within 48 hours after birth, but it is opposite in phase to that observed in the adult rat. The reversal of the adult pattern occurs 21 to 23 days after birth and may represent a response to a change both in the eating pattern and in the amount of protein eaten.

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