Virus-Like Particles in the Spiral Ganglion of the Guinea Pig Cochlea

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Science  27 Dec 1968:
Vol. 162, Issue 3861, pp. 1485-1487
DOI: 10.1126/science.162.3861.1485


Double-walled spherical particles 100 millimicrons in diameter were accidentally discovered in the cytoplasm of spiral ganglion neurons of apparently healthy guinea pigs with normal startle responses. These particles in some ways resemble viruses of the herpes group and may represent a latent form of neuronal infection.

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