Microtubules in Brain Homogenates

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Science  10 Jan 1969:
Vol. 163, Issue 3863, pp. 187-188
DOI: 10.1126/science.163.3863.187


Microtubules from neurons are preserved in homogenates of mammalian brain by medium containing organic solvents at acidic pH. By means of negative staining and electron microscopy, the relative concentration of microtubules in suspensions can be assayed. Microtubules from brain have a filamentous and substructure.

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