Deoxycytidine and Radiation Response: Exceedingly High Deoxycytidine Aminohydrolase Activity in Human Liver

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Science  10 Jan 1969:
Vol. 163, Issue 3863, pp. 191-192
DOI: 10.1126/science.163.3863.191


The activity of deoxycytidine aminohydrolase in the liver of various species including man was investigated. An enormously high activity was found in human liver. This fact explains the extraordinarily low level of deoxycytidine in human urine in comparison with that of other tested species. The suitability of deoxycitidinuria as a biochemical indicator of postirradiation damage in man remains, therefore, an open question.

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