Adrenergic Blood Pressure Responses in the Shark

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Science  24 Jan 1969:
Vol. 163, Issue 3865, pp. 395-397
DOI: 10.1126/science.163.3865.395


Both nurse and lemon sharks recovered slowly from the pressor effect of epinephrine and from the depressor effect of isoproterenol. The recovery time increased with the dose of epinephrine. Grading of dosage and the use of dibenzyline revealed that these species exhibit alpha and beta adrenergic vascular responses in a manner qualitatively similar but quantitatively dissimilar to that for mammals.

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