Adrenal Tyrosine Hydroxylase: Compensatory Increase in Activity after Chemical Sympathectomy

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Science  31 Jan 1969:
Vol. 163, Issue 3866, pp. 468-469
DOI: 10.1126/science.163.3866.468


Destruction of peripheral sympathetic nerve endings with 6-hydroxydopamine causes a disappearance of cardiac tyrosine hydroxylase, accompanied by a twofold increase in adrenal tyrosine hydroxylase and a small increase in phenyl-ethanolanine-N-methyl transferase. No change in adrenal catecholamine content occurs under these conditions.

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