Mechanism and Prevention of Fixed High Vascular Resistance in Autografted and Allografted Lungs

See allHide authors and affiliations

Science  14 Feb 1969:
Vol. 163, Issue 3868, pp. 699-701
DOI: 10.1126/science.163.3868.699


The fixed vascular resistance observed in tranisplanted Ilunlgs and attriblted to denervation can be avoided by angioplastic wideniing of the pulmonary artery anastotosis. With distenisible arterial anrastomoses, aultografted an, d allografted Ilunzgs vasodilate niormzally with inicreased flow and cani sutstaini dogs whose contralateral pulmonary artery is ligated imumediately after lutng transplanitation.

Stay Connected to Science