Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome

See allHide authors and affiliations

Science  21 Feb 1969:
Vol. 163, Issue 3869, pp. 826-828
DOI: 10.1126/science.163.3869.826


Monosodium L-glutamate is the cause of the Chinese restaurant syndrome and can precipitate headaches. In appropriate doses it causes burning sensations, facial pressure, and chest pain. These are pharmacological effects obeying a dose-effect relationship. There is considerable variation in oral threshold does among individuals.

Stay Connected to Science