Mitotic Division in Pancreatic Beta Cells

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Science  28 Feb 1969:
Vol. 163, Issue 3870, pp. 941-943
DOI: 10.1126/science.163.3870.941


Successful expansion of the islet cell mass occurs in genetically diabetic mice (C57 Bl/Ks-dbdb) following a period of dietary restriction, in the absence of a population of precursor cells. Differentiated cells that synthesize insulin retain the capability of undergoing mitotic division.

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