Diffusive and Convective Flow Across Membranes: Irreversible Thermodynamic Approach

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Science  28 Feb 1969:
Vol. 163, Issue 3870, pp. 944-945
DOI: 10.1126/science.163.3870.944


The experimentally verified hydrodynamic approach to a description of diffusive and convective flow of solute across mutual membrane pathways is compared with the phenomenological equation resulting from the application of irreversible thermodynamics. Inherent nonlinearities in this equation severely, if not absolutely, limit its usefulness.

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