Do Trehalose and Trehalase Function in Renal Glucose Transport?

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Science  07 Mar 1969:
Vol. 163, Issue 3871, pp. 1075-1076
DOI: 10.1126/science.163.3871.1075


Maximum catalytic capacity for renal trehalase varied from 20 micromoles (of glucose produced per minute per gram of fresh tissue) for the armadillo down to zero for the rat, the cat, most turtles, fishes, and all birds and snakes investigated. Labeled trehalose could not be demonstrated in the kidney of the rabbit and the rat after injection with labeled glucose. These data do not support the hypothesis that trehalase and trehalose function in the transport of glucose through the kidney.

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