Potassium Ion: Is the Bulk of Intracellular K+ Adsorbed?

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Science  21 Mar 1969:
Vol. 163, Issue 3873, pp. 1335-1336
DOI: 10.1126/science.163.3873.1335


When a major portion of the intracellular K+ in frog muscle is reversibly replaced by Na+, the extra Na+ gained by the cells does not show the nuclear magnetic resonance signal that free Na+ does. The data contradict the membrane theory but are in accord with the concept that the bulk of intracellular K+ is adsorbed.

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