Crystal and Molecular Structure of a Thymine-Thymine Adduct

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Science  11 Apr 1969:
Vol. 164, Issue 3876, pp. 183-184
DOI: 10.1126/science.164.3876.183


Thymine-thymine adduct is a product isolated from thymine irradiated with ultraviolet light in frozen aqueous solution. This compound is presumably formed through the rearrangement of an initial photoproduct. Single crystal x-ray diffraction analysis has confirmed the molecular formula of the adduct, 5-hydroxy-6-4'-(5'-methylpyrimid-2'-one)-dihydrothymine, except for the possibility of a hydrogen atom on the 3' nitrogren rather than the 1' nitrogen, and has established the stereoconfiguration of the molecule.

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