Oyster Ciliary Inhibition by Cystic Fibrosis Factor

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Science  18 Apr 1969:
Vol. 164, Issue 3877, pp. 325-326
DOI: 10.1126/science.164.3877.325


Ciliary inhibition in oysters serves as an assay in identifying a serum factor in cystic fibrosis patients and heterozygotes. Seriums from 47 patients With cystic fibrosis antd 19 heterozygotes caused ciliary cessation within 35 minutes, whereas serums from only 2 of 64 individuals without cystic fibrosis inhibited ciliary activity within this time.

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