Luteinizing Hormone: Action on the Graafian Follicle in vitro

See allHide authors and affiliations

Science  16 May 1969:
Vol. 164, Issue 3881, pp. 846-847
DOI: 10.1126/science.164.3881.846


Graafian follicles, dissected intact from the rabbit ovary and incubated for 40 minutes with luteinizing hormone, developed into corpora lutea when autotransplanted under the kidney capsule. Follicles incubated with follicle-stimulating hormone or without hormone degenerated and failed to luteinize. Direct exposure of the mammalian follicle to luteinizing hormone initiates luteinization and formation of the corpus luteum.

Stay Connected to Science