Postsynaptic Membrane Response Predicted from Presynaptic Input Pattern in Lobster Cardiac Ganglion

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Science  30 May 1969:
Vol. 164, Issue 3883, pp. 1080-1082
DOI: 10.1126/science.164.3883.1080


Given the pattern of impulses impinging on a neuron, it should be possible to predict its output firing pattern if enough is known about pre- and postsynaptic properties. A quantitative reproduction of the first part of this input-output conversion is reported, namely the translation of input pattern into a sequence of postsynaptic membrane potential variations.

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