Glycolipid and Mucopolysaccharide Abnormality in Fibroblasts of Fabry's Disease

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Science  27 Jun 1969:
Vol. 164, Issue 3887, pp. 1522-1523
DOI: 10.1126/science.164.3887.1522


Cultures of skin fiibroblasts from a patient with Fabry's disease showed an accumulation of the glycolipid, galactosyl-galactosyl-glucosyl ceramide. Such cells also showed metachromasia on staining with toluidine blue and a markedly elevated acid mucopolysaccharide content.

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