Tadpole Antibodies against Frog Hemoglobin and Their Effect on Development

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Science  04 Jul 1969:
Vol. 165, Issue 3888, pp. 67-69
DOI: 10.1126/science.165.3888.67


Rana catesbeiana tadpoles immunized with the main hemoglobin component of the adult frog of the same species produced precipitating and agglutinating antibodies against the immunogen. After natural metamorphosis, the immunized froglets have as their only major hemoglobin a protein immunologically and electrophoretically different from the major hemoglobin of control froglets.

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