Renin-Aldosterone System in Parkinson's Disease

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Science  18 Jul 1969:
Vol. 165, Issue 3890, pp. 291-292
DOI: 10.1126/science.165.3890.291


Low blood pressure is frequent in the akinetic form of Parkinson's disease. A low renin activity in plasma as well as a low rate of aldosterone secretion is demonstrated in these patients. Renin activity in the plasma is further decreased by treatment with L-dihy-droxyphenylalanine, thus partially accouinting for the hypotensive episodes seen with this form of therapy.

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