Potentially Lethal Radiation Damage: Repair by Mammalian Cells in Culture

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Science  01 Aug 1969:
Vol. 165, Issue 3892, pp. 490-492
DOI: 10.1126/science.165.3892.490


Less than optimum conditions with regard to cell division after x-irradiation provide the necessary environment in which mammalian cells can repair potentially lethal radiation damage. The kinetics of repair suggest that, during the repair process, a transient, unstable cellular state occurs which prevents cell division in complete growth medium. The capacity for repair appears to be dependent on cell age.

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