Carcinoma of the Cervix: Deficiency of Nexus Intercellular Junctions

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Science  08 Aug 1969:
Vol. 165, Issue 3893, pp. 597-598
DOI: 10.1126/science.165.3893.597


Intercellar junctions where cell membranes are in intimate contact (nexuses) are very abundant in the epithelium of normal human cervix. Squamous carcinoma cells are deficient in nexuses although a rare nexus is seen. Nexuses may be involved in normal growth regulation, while a deficiency of nexuses may be related to the invasive property of malignant growth.

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