Rats Enriched with Odd-Carbon Fatty Acids: Maintenance of Liver Glycogen during Starvation

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Science  22 Aug 1969:
Vol. 165, Issue 3895, pp. 811-813
DOI: 10.1126/science.165.3895.811


In young rats a diet containing triundecanoin as the major source of fat produces substantial enrichment of adipose tissue triglycerides with undecanoate and higher fatty acids with odd-numbered carbons. The terminal three-carbon residues arising from beta-oxidation of these acids are glucogenic and help to counteract the decreases in liver glycogen and serum glucose ordinarily induced by prolonged fasting.

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