Plasmodium malariae: Transmission from Monkey to Man by Mosquito Bite

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Science  29 Aug 1969:
Vol. 165, Issue 3896, pp. 918-919
DOI: 10.1126/science.165.3896.918


Anopheles freeborni mosquitoes were infected by feeding on New World monkeys, Aotus trivirgatus, infected with a Nigerian strain of Plasmodium malariae. The infection was passed to human volunteers through the bites of these mosquitoes, demonstrating the practicability of using a simian host for infection of mosquitoes with a third species of human malaria parasite and of the use of such mosquitoes to transmit the infection from monkey to man.

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